Cirrhosis occurs when liver disease has damaged the cells in the liver and caused scar tissue to form.
What is Pediatric Cirrhosis?
When liver disease has advanced and caused scar tissue to form, cirrhosis can result. The scar tissue blocks blood flow, which leads to waste products building up in the child’s body. Therefore, the liver cannot perform its normal functions.
Many people think of cirrhosis occurring due to a history of alcoholism. While this is sometimes a contributing factor in adults with cirrhosis, children can develop the condition for a variety of other reasons.
What are the signs and symptoms of Pediatric Cirrhosis?
Infections in the abdomen
Feeling confused or unusually forgetful
Loss of body hair
Reddened palms of the hands
Swelling of the legs and abdomen
Urine that is dark in color
Wounds that take unusually long to heal
What are the causes of Pediatric Cirrhosis?
Causes of cirrhosis in children can include:
Alpha1-antitrypsin deficiency - hereditary condition that can lead to lung and liver disease
Autoimmune hepatitis — inflammation of the liver caused by the body’s immune system mistakenly attacking the liver
Bile duct diseases — affect the tube that carries bile from the gallbladder to the small intestine during the normal course of digestion
Exposure to certain drugs and toxins — including methotrexate (medication used to treat cancer), rheumatoid arthritis and psoriasis) and high levels of vitamin A
Fatty liver disease — group of conditions that affect the liver of a person without a history of alcoholism
Glycogen storage disease — condition in which a child’s body is unable to process or store the energy found in foods
Hepatitis B — viral infection that affects the liver and causes both acute (short-term) and chronic (ongoing) complications
Hepatitis C — viral infection that leads to inflammation of the liver and other related complications
Tyrosinemia — genetic condition that causes problems breaking down a specific amino acid – called tyrosine – that is found in most sources of protein
Wilson’s disease — hereditary condition in which excessive amounts of copper accumulates in a child’s organs
Pediatric Cirrhosis Doctors and Providers