Hypoxic-ischemic encephalopathy (intrapartum asphyxia - HIE)

What is hypoxic-ischemic encephalopathy (intrapartum asphyxia - HIE)?

Hypoxic-ischemic encephalopathy (HIE) is a brain injury that occurs when a baby’s brain does not receive enough oxygen during birth. The condition is also sometimes called intrapartum asphyxia. It is the most common cause of severe brain injury and death in newborns.

Babies who have hypoxic-ischemic encephalopathy may experience life-long problems, such as:

• Cognitive disorders
• Developmental delay
• Neurological problems
• Problems with motor development

Hypoxic-ischemic encephalopathy may be mild, moderate or severe. The amount and type of brain damage depends on how long the baby is without oxygen. 

What are the signs and symptoms of hypoxic-ischemic encephalopathy (intrapartum asphyxia - HIE)?

The signs of hypoxic-ischemic encephalopathy are not always seen right away. Parents and doctors may notice delayed development and neurological problems as the child grows.

Some symptoms that may be seen immediately after birth include:

• Heart problems
• Kidney problems
• Liver problems
• Lung problems
• Organ failure
• Seizures