Tiffany Renea Simms-Waldrip, MD
Pediatric Hematologist/Oncologist
Associate Professor at UT Southwestern Medical Center
- Languages Spoken:
- English
Biography
Tiffany Simms-Waldrip, M.D., is a hematologist and oncologist at Children’s Health℠ who specializes in hematopoietic stem cell transplant (HSCT), with a special interest in patients with bone marrow failure. She is also an Assistant Professor of pediatrics at UT Southwestern Medical Center.
After earning her medical degree at Texas Tech University Health Sciences Center, Dr. Simms-Waldrip completed a pediatric residency as well as a hematology and oncology fellowship at the University of California, Los Angeles.
During medical school and residency, I was drawn to the field of oncology. I was intrigued by the pathophysiology of cancer and developed a strong connection to that patient population.
“During medical school and residency, I was drawn to the field of oncology. I was intrigued by the pathophysiology of cancer and developed a strong connection to that patient population,” Dr. Simms-Waldrip said.
During her fellowship in pediatric hematology/oncology, Dr. Simms-Waldrip discovered a passion for hematopoietic stem cell transplant.
Dr. Simms-Waldrip has specific research interests in evaluating the role of commensal microbial flora in the development of acute intestinal graft-versus-host disease (GVHD) and identifying improved diagnostic and therapeutic options for complications of HSCT, specifically GVHD and hepatic veno-occlusive disease (VOD).
Dr. Simms-Waldrip has been an American Society for Transplantation and Cellular Therapy Clinical Research Training Scholar and received a grant from the National Institutes of Health for developmental hematology training.
With a husband and two young sons, Dr. Simms-Waldrip doesn’t have much alone time, but when she does, she likes to run, do Pilates, or yoga. Her time away from work is spent with her family, whose hobbies have become her hobbies – she is an enthusiastic sports mom.
“I love doing anything with them that puts smiles on their faces,” she said.
Education and Training
- Medical School
- Texas Tech University Health Sciences Center at Lubbock (2004)
- Residency
- University of California at Los Angeles (2007), Pediatrics
- Fellowship
- University of California at Los Angeles (2010), Pediatric Hematology/Oncology
- Board Certification
- American Board of Pediatrics/Hematology-Oncology
Conditions
- Anaplastic astrocytoma
- Cancer
- Ependymoma
- Ewing sarcoma
- Glioblastoma
- Hepatoblastoma (liver cancer)
- Leukemia
- Lymphoma
- Medulloblastoma
- Neuroblastoma
- Non-rhabdomyosarcoma soft tissue sarcoma
- Osteosarcoma
- Pilocytic astrocytoma
- Retinoblastoma
- Rhabdomyosarcoma
- Thalassemia
- Wilms tumor (nephroblastoma)
- Immunodeficiency
Departments and Programs
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Research Interests
- Graft-versus-host disease
- Hematopoiesis
- Transplantation in bone marrow failure syndromes
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Publications
- Volumetric Modulated Arc Therapy Enabled Total Body Irradiation (VMAT-TBI): Six-year Clinical Experience and Treatment Outcomes. Zhang-Velten ER, Parsons D, Lee P, Chambers E, Abdulrahman R, Desai NB, Dan T, Wardak Z, Timmerman R, Vusirikala M, Patel P, Simms-Waldrip T, Aquino V, Koh A, Tan J, Iqbal Z, Zhang Y, Reynolds R, Chiu T, Joo M, Hrycushko B, Ouyang L, Lamphier R, Yan Y, Jiang SB, Kumar KA, Gu X, Transplant Cell Ther 2021 Nov
- Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization. Fan D, Coughlin LA, Neubauer MM, Kim J, Kim MS, Zhan X, Simms-Waldrip TR, Xie Y, Hooper LV, Koh AY. Nature Medicine. 2015 Jul; 21(7):808-14.
- Invasive fungal infections in pediatric hematopoietic stem cell transplant patients. Simms-Waldrip T, Rosen G, Nielsen-Saines K, Ikeda A, Brown B, Moore T. Infectious Diseases. 2015 Apr; 47(4):218-24.
- Dramatic response to rituximab in a child with severe cold autoimmune hemolytic anemia arising after allogeneic hematopoietic SCT, Simms-Waldrip T, Ikeda A, Goldfinger D, Moore T, Yuan S. Bone Marrow Transplantation 2009 1-2
- Role of the Aggresome Pathway in Cancer: Targeting the garbage disposal system in cells., Rodriguez-Gonzalez A, Lin T, Ikeda AK, Simms-Waldrip T, Fu C, Sakamoto KM. Cancer Research April 2008 68(8) 2557-2560
- Targeting the aggresome pathway in hematologic malignancies, Simms-Waldrip T, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Fu C, Sakamoto KM. Molecular Genetics and Metabolism 2008 94 283-286
- Molecular targets and the treatment of myeloid leukemia., Ikeda AK, Shankar DB, Watanake M, Tamanoi F, Simms-Waldrip T, Moore TB, Sakamoto KM. Molecular Genetics and Metabolism July 2006 88(3) 216-24
- FMS-like tyrosine kinase 3 in normal hematopoiesis and acute myeloid leukemia., Parcells B, Ikeda AK, Simms-Waldrip T, Moore TB, Sakamoto KM. Stem Cells May 2006 24(5) 1174-84
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Professional Activities
- American Society for Transplantation and Cellular Therapy (2010)
- American Society of Pediatric Hematology/Oncology (2009-2012)
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Awards and Honors
- ASBMT Clinical Research Training Scholar (2011)
- NIH T32 Developmental Hematology Training Grant (2008)
- AAP Resident Research Grant (2006)
- Magna Cum Laude, Texas Christian University (2000)