Pediatric Caudal Regression Syndrome

What are the signs and symptoms of Pediatric Caudal Regression Syndrome?

• Abnormalities of the kidneys, including the absence of one kidney (renal agenesis) or being located in the wrong area (misplaced kidney or ectopic kidney)
• Abnormalities of the spine
• Cleft lip or cleft palate (holes or spaces in lips or roof of mouth)
• Clubfoot (twisted foot or feet at birth) or webbed skin on the back of the knees
• Failure of the bladder to completely empty (neurogenic bladder)
• Increased urinary frequency
• Indentation on the skin of the lower back (sacral dimple)
• Ineffective bladder and bowel control
• Narrowing of the hips
• Reduced muscle mass in the legs
• Underdeveloped, flattened muscles of the buttocks

What are the causes of Pediatric Caudal Regression Syndrome?

Genetic or environmental factors can cause caudal regression. Babies whose mother has diabetes are at a higher risk of developing the condition.