Matthias Tilmann Florian Wolf, MD
Pediatric Nephrologist
Assistant Professor at UT Southwestern Medical Center
- Languages Spoken:
- English,
Biography
Matthias Wolf, M.D., is a pediatric nephrologist at Children’s Health℠ who specializes in kidney stones, cystic kidney disease, uromodulin-storage disease/nephronophthisis, renal tubular acidosis and electrolyte, magnesium and calcium abnormalities.
I hope that one day my research efforts will pay off by improving my patients' lives.
After earning his medical degree from Johannes Gutenberg University Mainz in Germany, Dr. Wolf completed several residencies in pediatrics and neonatal-perinatal medicine at children’s hospitals in Germany and the U.S. He also completed two fellowships in research at the University of Michigan Hospitals and Health Centers in Ann Arbor, Michigan, and a pediatric nephrology fellowship at Children's Medical Center Dallas.
Dr. Wolf's clinical and research interests include regulation of renal ion channels by urinary proteins, the impact of ion channel dysregulation on the development of diabetes mellitus, the genetics of kidney disorders, kidney stones and hypercalciuria (impact of urinary proteins) and treatment for uromodulin storage disease.
"I really appreciate the interactions with my patients," Dr. Wolf says. "They inspire and motivate me to improve patient outcomes by performing research. I enjoy being at the interface between patient care and research. I hope that one day my research efforts will pay off by improving my patients' lives."
Dr. Wolf enjoys spending his free time with his cats, biking, hiking in West Texas, attending classical concerts or an opera, visiting an art exhibition at the Kimbell Art Museum or going to a beer garden.
Education and Training
- Medical School
- Johannes Gutenberg Universitat Mainz (1999)
- Internship
- Ludwig-Maximilians-Universitat Munich (1999), Internal Medicine
- Residency
- UT Southwestern - Children's Medical Center (2009), Pediatrics
University Children's Hospital Cologne Germany (2006), Pediatrics
University Children's Hospital, Charite, Berlin (2004), Neonatal-Perinatal Medicine
University Children's Hospital, Freiburg Germany (2002), Pediatrics
Benjamin Franklin Childrens Hospital (2001), Pediatrics
University Children's Hospital Erlangen-Nuremberg (2000), Pediatrics - Fellowship
- UT Southwestern - Children's Medical Center (2012), Pediatric Nephrology
University of Michigan Hospitals (2007), Research
University of Michigan Hospitals (2004), Research - Board Certification
- American Board of Pediatrics/Nephrology
Conditions
- Acid-base and Electrolyte Disorders
- Acute Glomerulonephritis
- Acute Kidney Injury
- Alport Syndrome
- Amyloidosis
- Berger's Disease (IgA Nephropathy)
- Chronic Kidney Disease (CKD)
- Congenital Kidney Abnormalities
- Cystinuria (Inherited Kidney Stone Disorder)
- Duplex Kidney
- Focal Segmental Glomerulosclerosis
- Glomerular Filtration Disorders
- Glomerulopathy
- Hematuria (Blood in Urine)
- Hemolytic Uremic Syndrome (HUS)
- High Blood Pressure (Hypertension)
- Horseshoe Kidney
- Hydronephrosis
- Hypercalcemia
- Kidney Failure
- Kidney Tumors
- Low Blood Pressure (Hypotension)
- Multicystic Dysplastic Kidney
- Nephrolithiasis (Kidney and Ureteral Stones)
- Nephrotic Syndrome
- Obstructive Uropathy
- Polycystic Kidney Disease (PKD)
- Proteinuria (Excess Protein in Urine)
- Recurrent Urinary Tract Infections (UTI)
- Urinary Tract Infections (UTI)
- Vesicoureteral Reflux (VUR)
Treatments
Departments and Programs
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Research Interests
- Inherited Disorders of Calcium, Phosphate, and Magnesium
- Inherited renal disease
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Publications
- Omental Arteriopathy in Primary Atypical Hemolytic Uremic Syndrome. Ellington N, Wolf MT, Kasten J, Rakheja D International journal of surgical pathology 2017 Mar 1066896917699703
- Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly. Braun DA, Rao J, Mollet G, Schapiro D, Daugeron MC, Tan W, Gribouval O, Boyer O, Revy P, Jobst-Schwan T, Schmidt JM, Lawson JA, Schanze D, Ashraf S, Ullmann JFP, Hoogstraten CA, Boddaert N, Collinet B, Martin G, Liger D, Lovric S, Furlano M, Guerrera IC, Sanchez-Ferras O, Hu JF, Boschat AC, Sanquer S, Menten B, Vergult S, De Rocker N, Airik M, Hermle T, Shril S, Widmeier E, Gee HY, Choi WI, Sadowski CE, Pabst WL, Warejko JK, Daga A, Basta T, Matejas V, Scharmann K, Kienast SD, Behnam B, Beeson B, Begtrup A, Bruce M, Ch'ng GS, Lin SP, Chang JH, Chen CH, Cho MT, Gaffney PM, Gipson PE, Hsu CH, Kari JA, Ke YY, Kiraly-Borri C, Lai WM, Lemyre E, Littlejohn RO, Masri A, Moghtaderi M, Nakamura K, Ozaltin F, Praet M, Prasad C, Prytula A, Roeder ER, Rump P, Schnur RE, Shiihara T, Sinha MD, Soliman NA, Soulami K, Sweetser DA, Tsai WH, Tsai JD, Topaloglu R, Vester U, Viskochil DH, Vatanavicharn N, Waxler JL, Wierenga KJ, Wolf MTF, Wong SN, Leidel SA, Truglio G, Dedon PC, Poduri A, Mane S, Lifton RP, Bouchard M, Kannu P, Chitayat D, Magen D, Callewaert B, van Tilbeurgh H, Zenker M, Antignac C, Hildebrandt F Nature genetics 2017 Aug
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Professional Activities
- International Pediatric Nephrology Association (2014)
- American Board of Pediatrics, Diplomate (2010)
- American Society for Nephrology (2009)
- American Medical Association (2008)
- American Academy of Pediatrics (2007)
- Society for Pediatric Nephrology, Germany (2004)
- German Society of Pediatrics (1999)
- American Physiological Society (2015)
- American Diabetes Association (2018)
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Awards and Honors
- D Magazine Best Pediatric Specialist 2018-2020
- Carl W. Gottschalk Research Scholar Grant 2014, American Society of Nephrology
- Junior Investigator Research Award, Children's Clinical Research Advisory Committee 2013, Children's Medical Center Dallas
- Awarded Best Oral Presentation, Third Annual Senior Fellows' Research Day 2012, UT Southwestern Medical Center
- Pediatric Resident Research Award 2007-2009, UT Southwestern Medical Center
